Publications & Presentations

The following are recent publications and presentations supported by the CHOP BDMC (2015-present):

Bold/underlined names are BDMC staff
Underlined names are CHOP Biostatistics Faculty

Publications

Mercer-Rosa L, Elci OU, Pinto N, Tanel R, Goldmuntz E (2018, Accepted). 22q11.2 Deletion Status and Perioperative Outcomes for Tetralogy of Fallot with Pulmonary Atresia and Multiple Aorto-Pulmonary Collateral Vessels. Pediatric Cardiology

DiLorenzo MP, Elci OU, Wang Y, Banerjee A, Sato T, Ky B, Goldmuntz E, Mercer-Rosa L (2018, Accepted). Longitudinal Changes in Right Ventricular Function in Tetralogy of Fallot in the Initial Years after Surgical Repair. Journal of the American Society of Echocardiography

Hopper RK, Wang Y, Dematteo V, SantoA, Kawut S, Elci O, Hanna BD, Mercer-Rosa L (2018). Right ventricular function mirrors clinical improvement with use of prostacyclin analogues in pediatric pulmonary hypertension. Pulmonary Circulation. doi: 10.1177/2045894018759247

Noonan K, Croughan P, Mollen C, Zlotnik S, Elci O, Tollefson D, Foster R, Morris-Compton S (2017, Accepted). Qualitative review as a tool for systems improvement: An examination of the Quality Service Review. Children and Youth Services Review Corresponding.

Niles DE, Nishisaki A, Sutton RM, Elci OU, Meaney PA, O'Connor KA, Leffelman J, Kramer-Johansen J, Berg RA, Nadkarni V. Improved Retention of Chest Compression Psychomotor Skills with Brief "Rolling Refresher" Training. Simul Healthc. 2017 Aug;12(4):213-219. doi: 10.1097/SIH.0000000000000228.

Russell S, Bennett J, Wellman JA, Chung DC, Yu Z, Tillman A, Wittes J, Pappas J, Elci O, McCague, S Cross D, Marshall KA, Walshire J, Kehoe TL, Reichert H, Davis M, Raffini L, George LA, Hudson FP, Dingfield L, Zhu X, Haller JA, Sohn EH, Mahajan VB, Pfeifer W, Weckmann M, Johnson C, Gewaily D, Drack A, Stone E, Wachtel K, Simonelli F, Leroy BP, Wright F, High KA, Maguire AM. Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65-mediated inherited retinal dystrophy: a randomized, controlled, open-label, phase 3 trial. Lancet. 2017 Jul 13. pii: S0140-6736(17)31868-8. doi: 10.1016/S0140-6736(17)31868-8.

Niles DE, Cines C, Insley E, Foglia EE, Elci OU, Skare C, Olasveengen T, Ades A, Posencheg M, Nadkarni V, Kramer-Johansen J. Incidence and characteristics of positive pressure ventilation delivered to newborns in a US tertiary academic hospital. Resuscitation. 2017 Jun;115:102-109. doi: 10.1016/j.resuscitation.2017.03.035.

Londono-Obregon C, Goldmuntz E, Davey BT, Zhang X, Slap GB, Kim YY. Adult CHD: the ongoing need for physician counselling about heredity and contraceptive options. Cardiol Young. 2017 May;27(4):671-676. doi: 10.1017/S1047951116001013. Epub 2016 Jul 7.

Bhat M, Mercer-Rosa L, Fogel MA, Harris MA, Paridon SM, McBride MG, Shults J, Zhang X, Goldmuntz E. Longitudinal changes in adolescents with TOF: implications for care. Eur Heart J Cardiovasc Imaging. 2017 Mar 1;18(3):356-363. doi: 10.1093/ehjci/jew272.

Fogel MA, Li C, Elci OU, Pawlowski T, Schwab PJ, Wilson F, Nicolson SC, Montenegro LM, Diaz L, Spray TL, Gaynor JW, Fuller S, Mascio C, Keller MS, Harris MA, Whitehead KK, Bethel J, Vossough A, Licht DJ. Neurological Injury and Cerebral Blood Flow in Single Ventricles Throughout Staged Surgical Reconstruction. Circulation. 2017 Feb 14;135(7):671-682. doi: 10.1161/CIRCULATIONAHA.116.021724.

Potts DA, Davis KF, Elci OU, Fein JA. A Vibrating Cold Device to Reduce Pain in the Pediatric Emergency Department: A Randomized Clinical Trial. Pediatr Emerg Care. 2017 Jan 24. doi: 10.1097/PEC.0000000000001041.

Mirman JH, Curry AE, Winston FK, Fisher Thiel MC, Pfeiffer MR, Rogers R, Elliott MR, Durbin DR. Parental influence on driver licensure in adolescence: A randomized controlled trial. Health Psychol. 2017 Mar;36(3):245-254. doi: 10.1037/hea0000444. Epub 2016 Dec 12.

Taubman B, McHugh J, Rosen F, Elci OU. Repeat Concussion and Recovery Time in a Primary Care Pediatric Office. J Child Neurol. 2016 Dec;31(14):1607-1610.

Taubman B, Rosen F, McHugh J, Grady MF, Elci OU. The Timing of Cognitive and Physical Rest and Recovery in Concussion. J Child Neurol. 2016 Dec;31(14):1555-1560.

Stallings VA, Schall JI, Maqbool A, Mascarenhas MR, Alshaikh BN, Dougherty KA, Hommel K, Ryan J, Elci OU, Shaw WA. Effect of Oral Lipid Matrix Supplement on Fat Absorption in Cystic Fibrosis: A Randomized Placebo-Controlled Trial. J Pediatr Gastroenterol Nutr. 2016 Dec;63(6):676-680.

Bennett J, Wellman J, Marshall KA, McCague S, Ashtari M, DiStefano-Pappas J, Elci OU, Chung DC, Sun J, Wright JF, Cross DR, Aravand P, Cyckowski LL, Bennicelli JL, Mingozzi F, Auricchio A, Pierce EA, Ruggiero J, Leroy BP, Simonelli F, High KA, Maguire AM. Safety and durability of effect of contralateral-eye administration of AAV2 gene therapy in patients with childhood-onset blindness caused by RPE65 mutations: a follow-on phase 1 trial. Lancet. 2016 Aug 13;388(10045):661-72. doi: 10.1016/S0140-6736(16)30371-3.

Mitchell JA, Chesi A, Elci O, McCormack SE, Roy SM, Kalkwarf HJ, Lappe JM, Gilsanz V, Oberfield SE, Shepherd JA, Kelly A, Grant SF, Zemel BS. Physical Activity Benefits the Skeleton of Children Genetically Predisposed to Lower Bone Density in Adulthood. J Bone Miner Res. 2016 Aug;31(8):1504-12. doi: 10.1002/jbmr.2872.

Mitchell JA, Chesi A, Elci O, McCormack SE, Roy SM, Kalkwarf HJ, Lappe JM, Gilsanz V, Oberfield SE, Shepherd JA, Kelly A, Grant SF, Zemel BS. Genetic Risk Scores Implicated in Adult Bone Fragility Associate With Pediatric Bone Density. J Bone Miner Res. 2016 Apr; 31(4):789-95. doi: 10.1002/jbmr.2744. Epub 2015 Dec 14.

Schall JI, Mascarenhas MR, Maqbool A, Dougherty KA, Elci O, Wang DJ, Altes TA, Hommel KA, Shaw W, Moore J, Stallings VA. Choline Supplementation With a Structured Lipid in Children With Cystic Fibrosis: A Randomized Placebo-Controlled Trial. J Pediatr Gastroenterol Nutr. 2016 Apr; 62(4):618-26.

Misfeldt AM, Kirsch RE, Goldberg DJ, Mascio CE, Naim MY, Zhang X, Mott AR, Ravishankar C, Rossano JW. Outcomes of Single-Ventricle Patients Supported With Extracorporeal Membrane Oxygenation. Pediatr Crit Care Med. 2016 Mar;17(3):194-202. doi: 10.1097/PCC.0000000000000616.

Nandi D, Lin KY, O'Connor MJ, Elci OU, Kim JJ, Decker JA, Price JF, Zafar F, Morales DL, Denfield SW, Dreyer WJ, Jefferies JL, Rossano JW. Hospital Charges for Pediatric Heart Failure-Related Hospitalizations from 2000 to 2009. Pediatr Cardiol. 2016 Mar; 37(3):512-8. doi: 10.1007/s00246-015-1308-0. Epub 2015 Dec 8.

Savla J, Lin KY, Pradhan M, Ruebner RL, Rogers RS, Haskins SS, Owens AT, Abt P, Gaynor JW, Shaddy RE, Rossano JW. Heart Retransplant Recipients Have Better Survival With Concurrent Kidney Transplant Than With Heart Retransplant Alone. J Am Heart Assoc. 2015 Dec 11; 4(12). pii: e002435. doi: 10.1161/JAHA.115.002435.

Lasa JJ, Rogers RS, Localio R, Shults J, Raymond T, Gaies M, Thiagarajan R, Laussen PC, Kilbaugh T, Berg RA, Nadkarni V, Topjian A. Extracorporeal-Cardiopulmonary Resuscitation (E-CPR) During Pediatric In-Hospital Cardiopulmonary Arrest is Associated with Improved Survival to Discharge: A Report from the American Heart Association's Get With the Guidelines® - Resuscitation Registry (GWTG-R). Circulation. 2015 Dec 3. pii: IRCULATIONAHA.115.016082. [Epub ahead of print]

Achuff BJ, Nicolson SC, Elci OU, Zuppa AF. Intraoperative dexmedetomidine reduces postoperative mechanical ventilation in infants after open heart surgery. Pediatr Crit Care Med. 2015 Jun; 16(5):440-7. doi: 10.1097/PCC.0000000000000382.

Fogel MA, Li C, Wilson F, Pawlowski T, Nicolson SC, Montenegro LM, Diaz, Berenstein L, Spray TL, Gaynor JW, Fuller S, Keller MS, Harris MA, Whitehead KK, Clancy R, Elci O, Bethel J, Vossough A, Licht DJ. Relationship of cerebral blood flow to aortic-to-pulmonary collateral/shunt flow in single ventricles. Heart 101(16) P 1325-31. 2015 Jun 5. doi: 10.1136/heartjnl-2014-307311.

Peyvandi S, Rychik J, Zhang X, Shea JA, Goldmuntz E. Preconceptual Folic Acid Use and Recurrence Risk Counseling for Congenital Heart Disease. Congenit Heart Dis. 2015 May-Jun;10(3):219-25. doi: 10.1111/chd.12206. Epub 2014 Jul 24.

Tebas P, Spitsin S, Barrett JS, Tuluc F, Elci O, Korelitz JJ, Wagner W, Winters A, Kim D, Catalano R, Evans DL, Douglas SD. Reduction of soluble CD163, substance P, programmed death 1 and inflammatory markers: phase 1B trial of aprepitant in HIV-1-infected adults. AIDS. 2015 May 15;29(8):931-9. doi: 10.1097/QAD.0000000000000638.

Mitchell JA, Chesi A, Elci O, McCormack SE, Kalkwarf HJ, Lappe JM, Gilsanz V, Oberfield SE, Shepherd JA, Kelly A, Zemel BS, Grant SF. Genetics of Bone Mass in Childhood and Adolescence: Effects of Sex and Maturation Interactions. J Bone Miner Res. 30(9): P1676-83. 2015 Mar 12. doi: 10.1002/jbmr.2508.

Wright SW, Steenhoff AP, Elci O, Wolfe HA, Ralston M, Kgosiesele T, Makone I, Mazhani L, Nadkarni VM, Meaney PA. Impact of contextualized pediatric resuscitation training on pediatric healthcare providers in Botswana. Resuscitation. 2015 Mar; 88:57-62. doi: 10.1016/j.resuscitation.2014.12.007.

Mercer-Rosa L, Paridon SM, Fogel MA, Rychik J, Tanel RE, Zhao H, Zhang X, Yang W, Shults J, Goldmuntz E. 22q11.2 deletion status and disease burden in children and adolescents with tetralogy of Fallot. Circ Cardiovasc Genet. 2015 Feb;8(1):74-81. doi: 10.1161/CIRCGENETICS.114.000819. Epub 2015 Jan 5.

Kaufman BD, Videon N, Zhang X, Harris MA, Shaddy RE, Goldmuntz E. Procollagen type III amino-terminal propeptide: a serum biomarker of left ventricular remodelling in paediatric dilated cardiomyopathy. Cardiol Young. 2015 Feb;25(2):228-36. doi: 10.1017/S1047951113001820. Epub 2013 Nov 6.

Wittlieb-Weber CA, Lin KY, Zaoutis TE, O'Connor MJ, Gerald K, Paridon SM, Shaddy RE, Rossano JW. Pediatric versus adult cardiomyopathy and heart failure-related hospitalizations: a value-based analysis. J Card Fail. 2015 Jan; 21(1):76-82. doi: 10.1016/j.cardfail.2014.10.011. Epub 2014 Oct 24.

Presentations/Abstracts

Sandi Amaral; Rachel Rogers; Christopher Paterno; Nina Foster; Justine Shults. Peers4PATH (Promoting Adolescent Transplant Health): a pilot study of peer mentoring in adolescent transplant recipients. Presented at Pediatric Academic Societies (PAS) 2017 Meeting, May 6 - 9, in San Francisco, CA, and at the 9th Congress of the International Pediatric Transplant Association (IPTA) 2017, May 27 – 30, in Barcelona, Spain.

Leah A. Goldberg, Lacey P. Gleason, Tanmay Bhamare, Adi Hirshberg, Sara L. Partington, Rachel Rogers, Emily Ruckdeschel, Sindhu K. Srinivas, Natalie Stokes, Lynda Tobin, Morgan Venuti, Lisa D. Levine, and Yuli Kim. Risk Assessment in Pregnant Women with Congenital Heart Disease. Presented at the American Heart Association (AHA) Scientific Sessions 2016, November 12 – 16, in New Orleans, LA.

Okatch H, Rogers R, Morales K, Chapman J, Marukutira T, Tshume O, Matshaba M, Gross R, Anabwani G, Lowenthal E. A longitudinal study to determine the effect of disclosure on adherence among HIV-infected adolescents in Botswana. International Association of Physicians in AIDS Care (IAPAC) 10th International Conference on HIV Treatment and Prevention Adherence. Miami, FL. June 28-30, 2015.

McCague, Sarah; Wellman, Jennifer; Yu, Fan-Fan; Thill, Satha; DiStefano-Pappas, Julie; Bennett, Jean; Cross, Dominique; Marshall, Kathleen; High, Katherine; Chung, Daniel C.  Mobility testing validation study - Using a novel, standardized mobility test to evaluate functional vision in patients with inherited retinal degeneration.  Annual Meeting for The Association for Research in Vision and Ophthalmology (ARVO). Denver, CO.  May 3-7, 2015.

Mitchell JA, Chesi A, Elci O, McCormack S, Roy S, Kalkwarf H, Lappe J, Gilsanz V, Oberfield S, Shepherd J, Kelly A, Zemel B, Grant SFA (Pending: March 2015). The Skeletal Benefits of Physical Activity in Childhood Are Dependent on Genetic Variation at Known Bone Density Loci. Endocrine Society (ENDO) Annual Meeting.  San Diego, CA.  March 5-8, 2015